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[Modafinil 200]

Le modafinil peut ГЄtre considГ©rГ© comme bГ©nГ©fique lorsqu'une personne est fatiguГ©e pour des raisons telles qu'un horaire chargГ©, le dГ©but de vacances ou le dГ©but d'un quart de travail. Le Modafinil a Г©tГ© dГ©veloppГ© dans les annГ©es 1970 par Michel Jouvet et les Laboratoires Lafon. Modafinil est disponible sous forme de comprimГ© Г  prendre quotidiennement. Le modafinil est particuliГЁrement efficace dans le traitement de la variante de type 1 de ce trouble. La plupart des gens, cependant, ont tendance Г  prendre 50 mg et peuvent rester Г©veillГ©s pendant un maximum de six heures. Des doses plus importantes de modafinil peuvent ГЄtre utilisГ©es si nГ©cessaire. п»їLes indications du modafinil, qui a Г©tГ© Г©tudiГ© pour ses propriГ©tГ©s pharmacocinГ©tiques, comprennent la somnolence associГ©e au travail postГ©, l'apnГ©e obstructive du sommeil, la narcolepsie et les troubles du sommeil liГ©s au travail postГ©.  Modvigil En Ligne [pr] Le modafinil n'est pas approuvГ© par la Food and Drug Administration (FDA) pour une utilisation comme activateur cognitif aux Г‰tats-Unis, mais il a Г©tГ© utilisГ© aux Г‰tats-Unis hors AMM. D'autres Г©tudes contrГґlГ©es ont rapportГ© des rГ©sultats positifs similaires, mais des recherches supplГ©mentaires sont nГ©cessaires pour confirmer les rГ©sultats. Il est largement prescrit pour les troubles du sommeil liГ©s au travail postГ©, le dГ©calage horaire et la somnolence associГ©e Г  la narcolepsie. Cela peut entraГ®ner davantage d'effets secondaires et augmenter les effets des amphГ©tamines. Le modafinil a une biodisponibilitГ© orale Г©levГ©e (F = 95 %) et est bien absorbГ©. Le modafinil peut Г©galement ГЄtre achetГ© sous forme de capsule, avec des doses de 1 Г  20 milligrammes. Alors qu'il Г©tait initialement vendu par les laboratoires Lafon, l'USFDA a accordГ© une licence de commercialisation exclusive Г  Sun Pharmaceutical Industries en 2002. En 1999, l'Agence europГ©enne des mГ©dicaments (EMA) a approuvГ© le Modafinil pour le traitement des troubles du sommeil liГ©s au travail postГ© (SWSD). Aux Г‰tats-Unis, oГ№ le modafinil est une substance contrГґlГ©e de l'annexe IV, il a Г©tГ© commercialisГ© pour une utilisation hors AMM afin d'amГ©liorer l'Г©veil. Comme la cafГ©ine, il stimule le SNC en augmentant les effets du neurotransmetteur dopamine dans le SNC. Le modafinil est gГ©nГ©ralement pris 400 mg avant le coucher. Il est utilisГ© pour traiter divers troubles du sommeil. Le modafinil agit pour inhiber la recapture de la dopamine et de la noradrГ©naline, provoquant ainsi une augmentation de leur concentration et une augmentation de l'Г©veil. Les effets d'amГ©lioration cognitive du modafinil ont Г©tГ© testГ©s Г  l'aide de tests cognitifs de dГ©pistage de drogues et de tests conГ§us pour mesurer la mГ©moire, l'attention et le temps de rГ©action. 
 
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